The 5 Best Digestive Enzymes of 2023 – Enhance Your Digestion for Optimal Health

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Abdul Hanan, BDM

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This article is based on scientific evidence, written by experts and fact checked by experts. Our team of experts strive to be objective, unbiased, honest and to present both sides of the argument. This article contains scientific references. Read more about our process.

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Digestive enzymes play a vital role in breaking down the food we eat, aiding in nutrient absorption, and promoting overall digestive health. These specialized proteins act as catalysts, speeding up chemical reactions in our gastrointestinal tract to efficiently break down complex nutrients into smaller, more readily absorbable molecules. Without these essential enzymes, our bodies would struggle to extract the necessary nutrients from our foods, leading to digestive issues and potential nutrient deficiencies. This article provides the info about 5 best digestive enzymes of 2023.

The human body naturally produces on of the best digestive enzymes in the salivary glands, stomach, pancreas, and small intestine. However, certain factors, such as age, diet, lifestyle, and certain medical conditions, can affect the body’s ability to produce sufficient quantities of these enzymes. As a result, many individuals may experience digestive discomfort, bloating, gas, or other related issues.

To address these concerns and improve digestive function, digestive enzyme supplements have gained popularity as a practical solution. These supplements provide a concentrated blend of specific enzymes to aid in the digestion of proteins, fats, carbohydrates, and fibers. Adding these supplements to your diet can support your digestive system, alleviate discomfort, and enhance nutrient absorption for overall better health.

While various digestive enzyme supplements are available on the market, choosing the right one that aligns with your specific needs and preferences is crucial. In this article, we will explore the five best digestive enzyme supplements 2023, their unique benefits and limitations, and how they can potentially benefit you in achieving optimal digestive health.

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With the growing awareness of digestive enzyme supplements and their potential impact on gut health, it’s essential to understand who might benefit the most from incorporating them into their daily regimen and who should exercise caution or seek medical advice before doing so. Additionally, we will delve into what to look for when selecting a digestive enzyme supplement, potential interactions with other medications or supplements, and recommended dosages for safe and effective usage. Remember, that not each and every supplement is classified as best digestive enzymes.

By the end of this comprehensive guide, you will thoroughly understand the best digestive enzyme supplements available in 2023, empowering you to make informed choices about improving your digestive health and overall well-being. Let’s explore the pros and cons of each digestive enzyme supplement to find the one that suits your digestive needs the best. Below is the list and Pros/Cons of 5 best digestive enzymes:

1) Enzymedica Digest Gold with ATPro

Enzymedica’s Digest Gold with ATPro is popular among users seeking optimal digestive support. It combines a potent blend of digestive enzymes with the patented ATPro technology to enhance enzyme activity and support overall gut health.


  • Effective in breaking down a wide range of foods, including proteins, fats, carbohydrates, and fibers.
  • ATPro technology boosts the supplement’s effectiveness, ensuring maximum nutrient absorption.
  • Suitable for individuals with gluten sensitivity or lactose intolerance.


  • Pricier compared to some other digestive enzyme supplements.
  • Now Super is on of the best digestive Enzymes available in the market.
  • Now Super Enzymes is a reliable and budget-friendly option, containing a comprehensive mix of enzymes to support digestion and nutrient assimilation.

2) Now Super Enzymes

Now Super Enzymes (one of the best digestive enzymes) is a reliable and budget-friendly option, containing a comprehensive mix of enzymes to support digestion and nutrient assimilation.


  • Contains a balanced blend of enzymes, including bromelain, pancreatin, and papain.
  • Offers good value for money.
  • Suitable for vegetarians.


  • Some users might experience mild stomach discomfort initially.
  • Garden of Life Organic Chewable Enzymes
  • Garden of Life’s Organic Chewable Enzymes provides a convenient and vegan-friendly option for those who prefer chewable tablets over capsules.

3) Garden of Life Organic Chewable Enzymes

Garden of Life’s Organic Chewable Enzymes provides a convenient and vegan-friendly option for those who prefer chewable tablets over capsules. Considered to be one of the best digestive enzymes in the present time,


  • Easy-to-take chewable tablets with a pleasant taste.
  • They are made with organic and non-GMO ingredients.
  • Free from artificial additives and fillers.


  • The dosage might not be sufficient for individuals with severe digestive issues.

4) Source Naturals Daily Essential Enzymes

Source Naturals Daily Essential & best digestive Enzymes is a versatile supplement that supports overall digestive health in different dietary scenarios.


  • It offers a blend of enzymes to break down various food types.
  • Available in vegetarian and vegan options.
  • Suitable for people following specific diets, such as gluten-free or dairy-free diets.


  • It may not be as potent as specialized enzyme supplements.

5) Doctor’s Best Digestive Enzymes

Doctor’s Best Digestive Enzymes is a well-rounded option with a mix of enzymes to aid digestion and improve nutrient absorption.


  • It contains a diverse range of enzymes to tackle different food components.
  • Free from gluten, soy, and GMOs.
  • It supports digestive health and may alleviate bloating and gas.


  • Some users may find the capsules difficult to swallow.

Will You Benefit from a Digestive Enzyme Supplement?

If you experience regular digestive discomfort, bloating, and gas or have a medical condition affecting your enzyme production, a digestive enzyme supplement could significantly improve your digestive health. These supplements can help break down complex nutrients into easily absorbable forms, reducing the burden on your digestive system.

Who May Not Benefit from Digestive Enzymes

While digestive enzyme supplements are generally safe for most individuals, some people may not benefit from them, including:

  • Those with acute pancreatitis or other severe gastrointestinal conditions should consult a healthcare professional before using digestive enzymes.
  • Pregnant or nursing women should seek medical advice before taking supplements.
  • Individuals on specific medications should discuss potential interactions with their healthcare provider.

What to Look for in a Digestive Enzyme Supplement

When selecting a digestive enzyme supplement, consider the following factors to choose the best digestive enzymes:

  • Enzyme Blend: Look for a product with a comprehensive blend of enzymes that can break down proteins, fats, carbohydrates, and fibers effectively.
  • Enzyme Activity: Check for supplements with high enzyme activity to ensure efficient digestion.
  • Dosage and Potency: Consider the potency and recommended dosage for your digestive needs.
  • Additional Ingredients: Avoid products with unnecessary additives or fillers that could cause adverse reactions.

Ingredients & Potential Interactions

Always review the ingredient list and consult your healthcare professional, especially if taking other medications, to avoid potential interactions.

How Much Is Too Much?

Follow the recommended dosage provided by the manufacturer or your healthcare professional. Excessive enzyme supplements might lead to unwanted side effects or interactions with other medications.

Digestive Enzymes Not Recommended

Avoid using digestive enzyme supplements if you have a known allergy to ingredients or if your healthcare professional advises against them due to specific health conditions.

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Tips for Using Best Digestive Enzymes Effectively

  • Take the supplement with meals to aid digestion effectively.
  • Store the product as per the manufacturer’s instructions to maintain its potency.
  • Monitor how your body responds to the supplement and adjust the dosage if needed.


Yes, digestive enzyme supplements are generally safe for most individuals. However, it’s essential to follow the recommended dosage and consult your healthcare professional if you have any underlying health conditions or are taking medications.

Digestive enzyme supplements are most effective when taken with meals to aid digestion. Taking them on an empty stomach may not provide the desired benefits.

While digestive enzyme supplements can support better digestion and nutrient absorption, they are not specifically designed for weight loss. For weight loss, focus on a balanced diet and regular exercise.

Individuals may sometimes experience mild side effects, such as stomach discomfort or diarrhea when starting a new digestive enzyme supplement. These effects are usually temporary and should subside as your body adjusts to the supplement. If you experience severe or persistent side effects, discontinue use and consult your healthcare professional.

The Bottom Line

Digestive enzyme supplements can be valuable for individuals seeking relief from digestive discomfort and enhanced nutrient absorption. The five best digestive enzymes of 2023, Enzymedica Digest Gold with ATPro, Now Super Enzymes, Garden of Life Organic Chewable Enzymes, Source Naturals Daily Essential Enzymes, and Doctor’s Best Digestive Enzymes, offer different benefits and cater to various preferences and needs. Remember to consult your healthcare professional before starting any new supplement regimen, especially if you have existing medical conditions or take medications regularly.

These wre the best digestive enzymes possible to collect from internet and parsed to your knowledge.

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How we reviewed this article

Trend Of Health has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy

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